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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f78063a49a7ca316ea90e25d5e9b3ea2cb6dbe836dfd4077aca6a28aeb8ed9b1' 
  AND token = 'ZmGfKiONdE7D2x6AgfT6rwUsFV4VUrqdJponp5+eOOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}