SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '725472dcc7ee6d3c6ede1c25e2b47bf9e49dbd24d1abbd8358096382ce6de107' 
  AND token = 'rRl4gbEV72rlN700oxVYoCjEmuy/j0EctYPJ+JEXzBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}