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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b4d6c9d1008e9368579f4bc3ca7275805f48637c90ffe270a1b23103393e9fd' 
  AND token = 'x9PVf62EYpDlbMmq5ti8jlPC51lsi+ZZ6D1tRZPhiSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}