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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e94f5e29c7c656ec534a412a82efec2d61e0f1079e5db2d30e7f55f2e26614d4' 
  AND token = 'pU1HDFhzknUHwfyRUpPTo+xeJGunW0JKQXzbhDsL/J8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}