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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23ba50b51a6935635b48112068837a27fbf73a05dcad71c10e80d89167509f45' 
  AND token = 'W5v3NoANgIA8OaAQpd2JUl1pHPQhn4e/mIx/OJCYm1M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}