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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c47e186dc4e385599b670239a27f0b4375922fab5a516f1c291e0f14940af91' 
  AND token = 'kwy20m0NC36sUEaUxHMO7AzYod/zoNk/EibA44mWrPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}