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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d3e3f9529b2a76024d9ac094ff869090863ef8c46ec22b29b555cc9003bd804' 
  AND token = 'NdCfTZt/THtAwJ3/Nle53IEczHmm/6y7o/2/kRUqNm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}