SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10fd12d4d39ca6c36b849c5dd1141b4035c1b119286448def27c405b8e942f5d' 
  AND token = 'ZDsA4lP4MkvvKmjb87X61nFJ2H+PdbgDDeEfgWVqeWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}