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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '243e3c8c2c2ffa840b71b11c6c87b0a1cb6c6cd6252e4ea85fdc5af927ba3735' 
  AND token = 'iXPRvfS+CORtTdBqGVZw6yybstdQvCSmKNOQA1PoxIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}