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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3a07e5309df330c390a5998fe42b0a25935502212f52e0acbe1efb8c35b4070' 
  AND token = 'M/jv4u4jO+w0cLX4otQzADCvtAdd6ijAqwhkDk7mtgU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}