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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae20464571643a081a8d9e9dd943fd5552dd164f73a1a9ea08c4658d94d5324b' 
  AND token = '+FbRSENQf3CcTDdZBILaRwaNoESfFKzaPbcnA+8ejQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}