SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e22655dc1cf8642abaa878ea1097e49b1433efd27054446d892da04c891a0e6a' 
  AND token = '/CP5EsrHjsyctiFIiozo6MlX4fvpxfKdrQV5c0zXC04=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}