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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b67362bb041f66116f1390354fe5f4c3aff09a240d78fedde4ce1b69d212bb97' 
  AND token = 'Fgf4S5AofPeMGolp6OKoTAVbJG0ifqfB0xGcvo09dQ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}