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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8260610905a04e963cbc733b70459c6407deeb16e08a4a8a2ff206e5ef6b303d' 
  AND token = 'QSMp56eSbBsKMAmV7hXXwerCE059TdxYQaw1OAYK3dg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}