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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5660a8df1d6f876dca65d1eeba75951ebe90f536124b52eae13e09e9a0251b7' 
  AND token = 'Ckr8ShA/A9+MoKqfhADlsn+/qFmOyxYaTvfsNn2Zay0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}