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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1e9b2e1191164d3623ad80db62291ca35d3c7f0c991a9ffca0b806a285653c0' 
  AND token = 'tX6gup/um9Iv94zh3uYN3PhEaADyqMmpMM3VjscmG/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}