SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ebd4d55f740b97e5bb4a8866ec0ce27b2cb587e5de349cc9f833da5e0ee7428' 
  AND token = 'sZ/nA7kJul5LKXGqK9zUPkV+fBL12oOGNzB+Pzj5ieU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}