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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45efcb580efd59e2e70dda03cda68c33b94813e1013729be95628a2e87c1ac40' 
  AND token = '9xbQqgUb0w1RXOND2uUQPlQ/MuhZv3UIEJ21lqQO5WA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}