SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70ded8376c1a4b510c2ac44e6594a88a6c3cd818176e57bc825661828d99c125' 
  AND token = 'FSVglUNaO06DHGd/Zn13tW5WwPsMYJV7DtFDBc6GcJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}