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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85e49dd2ad18cc8fd13ab6021c2ea04a981aa6ec4a946235ab038b578f2094f3' 
  AND token = 'mvpbO8u0S0LgcXtUjS3vYlLmo4PzOVQjwpDRWWa5y4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}