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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b852b60a0b570820efbd0ae543490fc6db67828a2f36f98b876e68df58888ea' 
  AND token = 'p/2e6O9GIU4Sm+CJyk/0iuwpqBTz87cO/rm9wj/G6CM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}