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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1275bf84cb680cc6beef046762aeb44acd415aad0fc7c65fb92daf9ec5e5b3c3' 
  AND token = 'FEUuyquWnveM2Ei8qBkKgeFufe9+KLY1U6L3Cde0mUc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}