SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45d7c7006b415d8ab47da45e6b22829d1b09753f41d8683170d2062f1501e79b' 
  AND token = 'BMqmmGKeH/nZ0d21lp9YL+2NSQY78rMMajVi5b0Mvmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}