SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '395a7b97ac09fabff3837c8ef16cc77560d1a91b9cb4a8b4b3bfc8587bbb5639' 
  AND token = 'JDS7ANt0ggRJgARTVSg1MJhoqV+5zzcei0oe72lNNmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}