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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8488012362fd745ea704b1734d57eab597f747a66878613746fe808121302c9f' 
  AND token = 'KBquGN8ia6oFdkjKNyPvZKY2413Zac8nbmGm/y2p1mo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}