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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1db53a0888f6c167bbd8dbf9c7bc4ad49ad4d2fec6172edf84d7c6f636763187' 
  AND token = '+u6EQp/jxY2e4QCxWoEfEp5fNtpuFkSQ04HYL7aIY2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}