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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2757feb670b3f5cf9ecf55cc622a19e346bdc7f4598650791aed513339d36561' 
  AND token = 'dF3Qs6nrVMa9lSamQ3wZ0/aZY+YzvClaTcIKq2Uk51Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}