SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e5627c0d33386d93ea10af88e7be74aec21306bb7b30c7a1c2462e8018fa31b' 
  AND token = 'cbwlm1PkPiJ/VKORLXBrV2djj4OR2cwdgYPxt4RZm24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}