SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8973601be3f0c1a9032fa6ed44c4f353a17ac1527c950eb414791c1ed5383480' 
  AND token = 'SDRlHe3o4i+822QtalZhY00300gp7HpRsdhacWAWTy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}