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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80d7ddf571f12d6bdae8ee4144f0cde3e4cbdd973edbfcb0def2f5e0f13ca823' 
  AND token = 'V+huWLDT7+apR0+6MbRAl6+8PhtXb4PhI4VQtL/bseQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}