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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0e830bd5e3a0b8aec81a1fc60c5c5bebddbde0c167a586833b8dd4501e1d844' 
  AND token = 'IDXQ1/4ThS5tc+mt4/YHm9JT8IuYOJjkIxMuhcHa1N4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}