SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4328769ef71d1b1c6a3f8017054c5abb122d29bd7ddb34a0965a1f4ebc62705' 
  AND token = 'Zq7aek3J+nWmjTSGpI7mFvSZaAYiGitm1mViiPFDqFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}