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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '292c5d0bcbf86d4fdeb8260c680ec0af858ce452db9d3ec4a01a0bf87187dac4' 
  AND token = 'NoMcbZMlN6aW7qkYI6U4UTbs2yQGOGl2XkISCNL+ihE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}