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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '129c54a3a5af3a532337a9fe62df9100a613ed86053a3995fc2cb7ff781f4276' 
  AND token = '3mt5aopIwsEMNNSevbIjTR5Jhuj3zOVLavxZ+R5wC3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}