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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a8bee708dd2f84bed5e82bb49ae97e0e06eba76b04afcaf91a48c02cee9a0e6' 
  AND token = 'TVIXZCoxl+9qecm4ZxxTA8PVBobWkNS3S5XUrRsN/L0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}