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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bdfb8e01f59e1fb18e1c4634c98d4e38c92d23d76926c92d946fda503b5be667' 
  AND token = 'ISysQk2MwAXJppgnFApiX0JIGX44r66minOUjPBM/pI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}