SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e143219996524df47095b6569d76449862006ee5fc197b2fa10a626e5c4c0a53' 
  AND token = '2Z1K5V8/xMMD3tSt/xIwxH6tkpVR7yy1+MtlP5bpGqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}