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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34f07b0f2e5c54b1b6908efe058bda1044a72121b56e69e5c7d0da992d343a36' 
  AND token = 'HHBlyOW9Zqh6//H5YR7thIM6FBUezi1OlFr5WmwZz2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}