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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e57989954f22b5f926096e41834e6a0cfd731d12c5d31f903b635fc70ab1acf' 
  AND token = 'pP5+aBIQM9Z/iknI8G27nFRvw8tIe2Lg6DjUaIlEv6w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}