SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50a27654aecf70f1e95bdbe4c0e7a6d90b30a3ed129fac1e1eaba658a2e9e930' 
  AND token = 'mvAut/1tNUEAemyhvW/vYlNrBOzDG4IxIRdlAwpbc2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}