SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c18e8301915d82c862896608adb91ebe0d3cc3b72e69697bb770d1b1c7f044ac' 
  AND token = 'WWDAC9aL9Zjd/sEPjoE21x4yKN9GFExvkrUJVs2NxVU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}