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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa4b17c64be5869202bd667b8f375f53aafa667369e935e90c4e0b21c1b59df0' 
  AND token = 'uHZKLdbDMHEuFHeqUKz8CfKBucRtjQZR35eTY7POLM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}