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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49fbe4a67ce2ee8be80573c9220574fd7fd86b272b5699b20d163d5f618ee43f' 
  AND token = 'oq49fj+8x6rym5FVpPgQlfQdn64Hljq1ePDi8gQllTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}