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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b57b2dbc9fa5594cc460e026632f7a033f28d6e26e71b4e19855325a98cdbae' 
  AND token = '8NmzPJz+c5AagZeaEUNxuR+dRJ5fH+YAf8IwOUbbMIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}