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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37264586d710f6d61413a075498ce354a5d1008720032203a975a07487f2b3c5' 
  AND token = '+xybaPnAEixa3Vad6+LDObnNCL4zejV8ouwZ0kWpgZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}