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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5b8abd1211196c56d4903868adc76adc573f956c8a3736e3459f930bf449aa7' 
  AND token = 'LIE6pGI2LUubiHdyiakESD2SimhaEtumGxgT5rPX7fs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}