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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '590467ced0420a3f29b0df1d0c202110d3ff98e5654b8323f43dc5ad17671ceb' 
  AND token = 'A5xIQ/j7WcmkjPYkdESK/BN7z+IhBpe2x6zunI/Yo58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}