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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41ea1584d1ca6e2a3d329229933d33d4942926c12c94af495e50b63751880e71' 
  AND token = '8X17mPzguu3ZYCSizPz4wgQ/kx1dkXBleZcY8veb1HE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}