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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a13018c6cfa93593c2aebea63e6233cb17da578eaf4723b01f5df5d09d754da7' 
  AND token = 'lsKy+37ITaV3PUbT3YWYNITgmgF2OkG00+7IyW02AGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}