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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5c4f3b18bc7ccdd52716741e8cb6b7ee140c62ab0321571a3a772dce06ac24a' 
  AND token = 'jI/NgOHM8ixMHaaPULIMqcHXghhTFhfwimg5KiTht2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}